Effect of Treatment with 5-Ethyl-2′-Deoxyuridine on Herpes Simplex Virus Encephalitis in Normal and Immunosuppressed Mice

5-Ethyl-2′-deoxyuridine (5-ethyl-dUrd), an analog of thymidine, was evaluated for its capacity to inhibit herpes simplex virus (HSV) replication in vitro and in vivo. The 50% effective dose concentration of 5-ethyl-dUrd for HSV types 1 and 2 (HSV-1 and -2) cultured in Vero cells was 6 and 9 μg/ml, r...

Полное описание

Библиографические подробности

Опубликовано в::	Antimicrob Agents Chemother
Главные авторы:	Davis, William B., Oakes, John E., Taylor, John A.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 1978
Предметы:	Pharmacology and Therapeutics
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352544/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/215081/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.14.5.743
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!