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Effect of Treatment with 5-Ethyl-2′-Deoxyuridine on Herpes Simplex Virus Encephalitis in Normal and Immunosuppressed Mice

5-Ethyl-2′-deoxyuridine (5-ethyl-dUrd), an analog of thymidine, was evaluated for its capacity to inhibit herpes simplex virus (HSV) replication in vitro and in vivo. The 50% effective dose concentration of 5-ethyl-dUrd for HSV types 1 and 2 (HSV-1 and -2) cultured in Vero cells was 6 and 9 μg/ml, r...

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Sábháilte in:
Sonraí bibleagrafaíochta
Foilsithe in:Antimicrob Agents Chemother
Príomhchruthaitheoirí: Davis, William B., Oakes, John E., Taylor, John A.
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: American Society for Microbiology (ASM) 1978
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352544/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/215081/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.14.5.743
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