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Optic atrophy 1 mediates mitochondria remodeling and dopaminergic neurodegeneration linked to complex I deficiency

Mitochondrial complex I dysfunction has long been associated with Parkinson's disease (PD). Recent evidence suggests that mitochondrial involvement in PD may extend beyond a sole respiratory deficit and also include perturbations in mitochondrial fusion/fission or ultrastructure. Whether and ho...

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Hlavní autoři: Ramonet, D, Perier, C, Recasens, A, Dehay, B, Bové, J, Costa, V, Scorrano, L, Vila, M
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524632/
https://ncbi.nlm.nih.gov/pubmed/22858546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.95
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