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Heme oxygenase-1 inhibits phosphorylation of the Helicobacter pylori oncoprotein CagA in gastric epithelial cells

The cytotoxin-associated gene A protein (CagA) plays a pivotal role in the etiology of Helicobacter (H.) pylori-associated gastric diseases. CagA is injected into the cytoplasm of host cells by a type IV secretion system, and is phosphorylated on tyrosine residues by the host enzyme c-Src. We previo...

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Bibliografische gegevens
Hoofdauteurs: Gobert, Alain P., Verriere, Thomas, de Sablet, Thibaut, Peek, Richard M., Chaturvedi, Rupesh, Wilson, Keith T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524338/
https://ncbi.nlm.nih.gov/pubmed/23051580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12039
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