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Control of solid tumor growth in mice using EGF receptor targeted RNA replicase-based plasmid DNA

Previously, it was shown that treatment of tumor-bearing mice with an RNA replicase-based plasmid that produces double-stranded RNA when transfected into tumor cells significantly inhibited the tumor growth. In the present study, the feasibility of further improving the anti-tumor activity of the RN...

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Detalhes bibliográficos
Principais autores: Rodriguez, B. Leticia, Li, Xinran, Kiguchi, Kaoru, DiGiovanni, John, Unger, Evan C., Cui, Zhengrong
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523886/
https://ncbi.nlm.nih.gov/pubmed/22296186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm.11.112
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