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Sprouty genes function in suppression of prostate tumorigenesis
Expression of Sprouty genes is frequently decreased or absent in human prostate cancer, implicating them as suppressors of tumorigenesis. Here we show they function in prostate tumor suppression in the mouse. Concomitant inactivation of Spry1 and Spry2 in prostate epithelium causes ductal hyperplasi...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3523874/ https://ncbi.nlm.nih.gov/pubmed/23150596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217204109 |
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