Suppression of Tak1 Promotes Prostate Tumorigenesis

Over 30% of primary prostate cancers contain a consensus deletion of an approximately 800 kb locus on chromosome 6q15.1. The MAP3K7 gene, which encodes TGF-β Activated Kinase-1 (Tak1), is a putative prostate tumor suppressor gene within this region whose precise function remains obscure. In this stu...

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Bibliografiset tiedot
Päätekijät: Wu, Min, Shi, Lihong, Cimic, Adela, Romero, Lina, Sui, Guangchao, Lees, Cynthia J., Cline, J. Mark, Seals, Darren F., Sirintrapun, Joseph S., McCoy, Thomas P., Liu, Wennuan, Kim, Jin Woo, Hawkins, Gregory A., Peehl, Donna M., Xu, Jianfeng, Cramer, Scott D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654674/
https://ncbi.nlm.nih.gov/pubmed/22467172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2724
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