GIRK channel modulation by assembly with allosterically regulated RGS proteins

G-protein–activated inward-rectifying K(+) (GIRK) channels hyperpolarize neurons to inhibit synaptic transmission throughout the nervous system. By accelerating G-protein deactivation kinetics, the regulator of G-protein signaling (RGS) protein family modulates the timing of GIRK activity. Despite m...

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Bibliografiske detaljer
Main Authors: Zhou, Hao, Chisari, Mariangela, Raehal, Kirsten M., Kaltenbronn, Kevin M., Bohn, Laura M., Mennerick, Steven J., Blumer, Kendall J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523866/
https://ncbi.nlm.nih.gov/pubmed/23169654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214337109
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