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Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression

Hypoxia-inducible factor 1 (HIF-1) activates transcription of genes encoding proteins that play key roles in breast cancer biology. We hypothesized that interaction of HIF-1 with epigenetic regulators may increase HIF-1 transcriptional activity, and thereby promote breast cancer progression. We repo...

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Detalhes bibliográficos
Main Authors: Luo, Weibo, Chang, Ryan, Zhong, Jun, Pandey, Akhilesh, Semenza, Gregg L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523832/
https://ncbi.nlm.nih.gov/pubmed/23129632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217394109
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