Mutations in DMRT3 affect locomotion in horses and spinal circuit function in mice

Locomotion in mammals relies on a central pattern-generating circuitry of spinal interneurons established during development that coordinates limb movement(1). These networks produce left–right alternation of limbs as well as coordinated activation of flexor and extensor muscles(2). Here we show tha...

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Main Authors: Andersson, Lisa S., Larhammar, Martin, Memic, Fatima, Wootz, Hanna, Schwochow, Doreen, Rubin, Carl-Johan, Patra, Kalicharan, Arnason, Thorvaldur, Wellbring, Lisbeth, Hjälm, Göran, Imsland, Freyja, Petersen, Jessica L., McCue, Molly E., Mickelson, James R., Cothran, Gus, Ahituv, Nadav, Roepstorff, Lars, Mikko, Sofia, Vallstedt, Anna, Lindgren, Gabriella, Andersson, Leif, Kullander, Klas
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523687/
https://ncbi.nlm.nih.gov/pubmed/22932389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11399
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