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Effect of N′-Methylnicotinamide on the Renal Accumulation and Reabsorption of Gentamicin in Rats

N′-methylnicotinamide, a substrate of the organic base transport system, reduced renal accumulation of [(14)C]gentamicin in rats by 15% and increased clearance by 25%, suggesting that gentamicin is not secreted by this mechanism.

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書誌詳細
主要な著者: Jerauld, R., Silverblatt, F. J.
フォーマット: Artigo
言語:Inglês
出版事項: 1978
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC352352/
https://ncbi.nlm.nih.gov/pubmed/149514
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