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Gentamicin Nephrotoxicity: Failure of Three Cephalosporins to Potentiate Injury in Rats

The possibility that gentamicin and cephalosporin antibiotics may act synergistically to produce nephrotoxicity was evaluated in an experimental model. Necrosis of the proximal tubules occurred when rats were treated with 60 to 120 mg/kg of gentamicin for 5 days but not when 15 to 20 mg/kg per day w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Harrison, William O., Silverblatt, Fredric J., Turck, Marvin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1975
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429289/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1180545/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.8.2.209
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