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Gentamicin Nephrotoxicity: Failure of Three Cephalosporins to Potentiate Injury in Rats

The possibility that gentamicin and cephalosporin antibiotics may act synergistically to produce nephrotoxicity was evaluated in an experimental model. Necrosis of the proximal tubules occurred when rats were treated with 60 to 120 mg/kg of gentamicin for 5 days but not when 15 to 20 mg/kg per day w...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Harrison, William O., Silverblatt, Fredric J., Turck, Marvin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1975
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429289/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1180545/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.8.2.209
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