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Structure-based drug screening for G protein-coupled receptors
G protein-coupled receptors (GPCRs) represent a large family of signaling proteins that includes many therapeutic targets; however, progress in identifying new small molecule drugs has been disappointing. The past four years have seen remarkable progress in the structural biology of GPCRs, raising t...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3523194/ https://ncbi.nlm.nih.gov/pubmed/22503476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2012.03.007 |
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