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A Role for Rac1 in Glycoprotein Ib-IX-mediated Signal Transduction and Integrin Activation
OBJECTIVE: The platelet receptor for von Willebrand factor (VWF), the glycoprotein Ib-IX (GPIb-IX) complex, mediates platelet adhesion at sites of vascular injury and transmits signals leading to platelet activation. VWF/GPIb-IX interaction sequentially activates the Src Family Kinase (SFK) Lyn, pho...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3523182/ https://ncbi.nlm.nih.gov/pubmed/22995516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.254920 |
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