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Hexa-D-Arginine treatment increases 7B2•PC2 activity in hyp-mouse osteoblasts and rescues the HYP phenotype

Inactivating mutations of PHEX/Phex underlie disease in patients with X-linked hypophosphatemia (XLH) and the hyp-mouse, a murine homologue of the human disorder. Although increased serum FGF-23 underlies the HYP phenotype, the mechanism(s) by which PHEX mutations inhibit FGF-23 degradation and/or e...

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書誌詳細
主要な著者: Yuan, Baozhi, Feng, Jian Q., Bowman, Stephen, Liu, Ying, Blank, Robert D., Lindberg, Iris, Drezner, Marc K.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523095/
https://ncbi.nlm.nih.gov/pubmed/22886699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1738
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