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Protection against Anthrax Toxemia by Hexa-d-Arginine In Vitro and In Vivo
The anthrax toxin protective antigen precursor is activated by proteolytic cleavage by furin or a furin-like protease. We present here data demonstrating that the small stable furin inhibitor hexa-d-arginine amide delays anthrax toxin-induced toxemia both in cells and in live animals, suggesting tha...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC343991/ https://ncbi.nlm.nih.gov/pubmed/14688144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.1.602-605.2004 |
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