Irreversible Effects of Serum Proteins on Beta-Lactam Antibiotics

The chromogenic cephalosporin nitrocefin (87/312) demonstrates rapid and visible instability to serum from many species. This phenomenon was distinct from serum binding, being significantly slower. Destruction of another cephalosporin, 10485, by serum appeared to account for some anomalous results d...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Antimicrob Agents Chemother
1. Verfasser:	O'Callaghan, Cynthia H.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1978
Schlagworte:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352300/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/27139/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.13.4.628
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