Irreversible Effects of Serum Proteins on Beta-Lactam Antibiotics

The chromogenic cephalosporin nitrocefin (87/312) demonstrates rapid and visible instability to serum from many species. This phenomenon was distinct from serum binding, being significantly slower. Destruction of another cephalosporin, 10485, by serum appeared to account for some anomalous results d...

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發表在:	Antimicrob Agents Chemother
主要作者:	O'Callaghan, Cynthia H.
格式:	Artigo
語言:	Inglês
出版:	American Society for Microbiology (ASM) 1978
主題:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352300/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/27139/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.13.4.628
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