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Complex regulation controls Neurogenin3 proteolysis

The ubiquitin proteasome system (UPS) is known to be responsible for the rapid turnover of many transcription factors, where half-life is held to be critical for regulation of transcriptional activity. However, the stability of key transcriptional regulators of development is often very poorly chara...

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Autors principals: Roark, Ryan, Itzhaki, Laura, Philpott, Anna
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522888/
https://ncbi.nlm.nih.gov/pubmed/23259061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20121750
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