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2’-Behenoyl-Paclitaxel Conjugate Containing Lipid Nanoparticles for the Treatment of Metastatic Breast Cancer

The aim of these studies was to develop a novel 2’-behenoyl-paclitaxel (C22-PX) conjugate nanoparticle (NP) formulation for the treatment of metastatic breast cancer. A lipophilic paclitaxel derivative C22-PX was synthesized and incorporated into lipid-based NPs. Free C22-PX and its NP formulation w...

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Autori principali: Ma, Ping, Benhabbour, S. Rahima, Feng, Lan, Mumper, Russell J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522796/
https://ncbi.nlm.nih.gov/pubmed/22902506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2012.08.009
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