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The Extent of Cardiac Myosin Binding Protein-C Phosphorylation Modulates Actomyosin Function in a Graded Manner
Cardiac myosin binding protein-C (cMyBP-C), a sarcomeric protein with 11 domains, C0-C10, binds to the myosin rod via its C-terminus, while its N-terminus binds regions of the myosin head and actin. These N-terminal interactions can be attenuated by phosphorylation of serines in the C1-C2 motif link...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3522762/ https://ncbi.nlm.nih.gov/pubmed/22752314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10974-012-9312-y |
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