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Molecular Mechanics of Cardiac Myosin Binding Protein-C in Native Thick Filaments
The heart's pumping capacity results from highly regulated interactions of actomyosin molecular motors. Mutations in the gene for a potential regulator of these motors, cardiac myosin binding protein-C (cMyBP-C), cause hypertrophic cardiomyopathy. However, cMyBP-C's ability to modulate car...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3561468/ https://ncbi.nlm.nih.gov/pubmed/22923435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1223602 |
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