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Molecular Mechanics of Cardiac Myosin Binding Protein-C in Native Thick Filaments

The heart's pumping capacity results from highly regulated interactions of actomyosin molecular motors. Mutations in the gene for a potential regulator of these motors, cardiac myosin binding protein-C (cMyBP-C), cause hypertrophic cardiomyopathy. However, cMyBP-C's ability to modulate car...

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Bibliografiske detaljer
Main Authors: Previs, M.J., Previs, S. Beck, Gulick, J., Robbins, J., Warshaw, D.M.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561468/
https://ncbi.nlm.nih.gov/pubmed/22923435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1223602
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