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Wax Ester Synthesis is Required for Mycobacterium tuberculosis to Enter In Vitro Dormancy

Mycobacterium tuberculosis (Mtb) is known to produce wax esters (WE) when subjected to stress. However, nothing is known about the enzymes involved in biosynthesis of WE and their role in mycobacterial dormancy. We report that two putative Mtb fatty acyl-CoA reductase genes (fcr) expressed in E. col...

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Détails bibliographiques
Auteurs principaux: Sirakova, Tatiana D., Deb, Chirajyoti, Daniel, Jaiyanth, Singh, Harminder D., Maamar, Hedia, Dubey, Vinod S., Kolattukudy, Pappachan E.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522743/
https://ncbi.nlm.nih.gov/pubmed/23272127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051641
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