Wax Ester Synthesis is Required for Mycobacterium tuberculosis to Enter In Vitro Dormancy

Mycobacterium tuberculosis (Mtb) is known to produce wax esters (WE) when subjected to stress. However, nothing is known about the enzymes involved in biosynthesis of WE and their role in mycobacterial dormancy. We report that two putative Mtb fatty acyl-CoA reductase genes (fcr) expressed in E. col...

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Main Authors: Sirakova, Tatiana D., Deb, Chirajyoti, Daniel, Jaiyanth, Singh, Harminder D., Maamar, Hedia, Dubey, Vinod S., Kolattukudy, Pappachan E.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522743/
https://ncbi.nlm.nih.gov/pubmed/23272127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051641
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