Tetraspanin CD82 Inhibits Protrusion and Retraction in Cell Movement by Attenuating the Plasma Membrane-Dependent Actin Organization

To determine how tetraspanin KAI1/CD82, a tumor metastasis suppressor, inhibits cell migration, we assessed which cellular events critical for motility are altered by KAI1/CD82 and how KAI1/CD82 regulates these events. We found that KAI1/CD82-expressing cells typically exhibited elongated cellular t...

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Detalhes bibliográficos
Main Authors: Liu, Wei M., Zhang, Feng, Moshiach, Simon, Zhou, Bin, Huang, Chao, Srinivasan, Kamalakkannan, Khurana, Seema, Zheng, Yi, Lahti, Jill M., Zhang, Xin A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522597/
https://ncbi.nlm.nih.gov/pubmed/23251627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051797
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