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Human Exonuclease 5 Is a Novel Sliding Exonuclease Required for Genome Stability
Previously, we characterized Saccharomyces cerevisiae exonuclease 5 (EXO5), which is required for mitochondrial genome maintenance. Here, we identify the human homolog (C1orf176; EXO5) that functions in the repair of nuclear DNA damage. Human EXO5 (hEXO5) contains an iron-sulfur cluster. It is a sin...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3522276/ https://ncbi.nlm.nih.gov/pubmed/23095756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.422444 |
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