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Extracellular Tau Levels Are Influenced by Variability in Tau That Is Associated with Tauopathies

Tauopathies are a class of neurodegenerative diseases marked by intracellular aggregates of hyperphosphorylated Tau. These diseases may occur by sporadic mechanisms in which genetic variants represent risk factors for disease, as is the case in Alzheimer disease (AD). In AD, cerebrospinal fluid (CSF...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Karch, Celeste M., Jeng, Amanda T., Goate, Alison M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522274/
https://ncbi.nlm.nih.gov/pubmed/23105105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.380642
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