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Silencing of Hint1, a novel tumor suppressor gene, by promoter hypermethylation in hepatocellular carcinoma

The Hint1 protein, a member of the histidine triad (HIT) family, is highly conserved in diverse species and ubiquitously expressed in mammalian tissues. Previous studies in mice provided evidence that Hint1 may be haplosufficient with respect to its function as a tumor suppressor. In the present stu...

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Hlavní autoři: Zhang, Yu-Jing, Wu, Hui-Chen, Shen, Jing, Li, Haiyang, Wang, Lin, Yu, Ming-Whei, Lee, Po-Huang, Weinstein, I. Bernard, Santella, Regina M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522093/
https://ncbi.nlm.nih.gov/pubmed/19081673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2008.10.042
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