Simultaneous modulation of the intrinsic and extrinsic pathways by simvastatin in mediating prostate cancer cell apoptosis

BACKGROUND: Recent studies suggest the potential benefits of statins as anti-cancer agents. Mechanisms by which statins induce apoptosis in cancer cells are not clear. We previously showed that simvastatin inhibit prostate cancer cell functions and tumor growth. Molecular mechanisms by which simvast...

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Detaylı Bibliyografya
Asıl Yazarlar: Goc, Anna, Kochuparambil, Samith T, Al-Husein, Belal, Al-Azayzih, Ahmad, Mohammad, Shuaib, Somanath, Payaningal R
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522038/
https://ncbi.nlm.nih.gov/pubmed/22974127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-409
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