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Asymmetric bioreduction of activated alkenes to industrially relevant optically active compounds

Ene-reductases from the ‘Old Yellow Enzyme’ family of flavoproteins catalyze the asymmetric reduction of various α,β-unsaturated compounds at the expense of a nicotinamide cofactor. They have been applied to the synthesis of valuable enantiopure products, including chiral building blocks with broad...

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Autori principali: Winkler, Christoph K., Tasnádi, Gábor, Clay, Dorina, Hall, Mélanie, Faber, Kurt
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier Science Publishers 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521962/
https://ncbi.nlm.nih.gov/pubmed/22498437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiotec.2012.03.023
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