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Unassembled CD147 is an endogenous endoplasmic reticulum–associated degradation substrate

Degradation of folding- or assembly-defective proteins by the endoplasmic reticulum–associated degradation (ERAD) ubiquitin ligase, Hrd1, is facilitated by a process that involves recognition of demannosylated N-glycans by the lectin OS-9/XTP3-B via the adaptor protein SEL1L. Most of our knowledge o...

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Détails bibliographiques
Auteurs principaux: Tyler, Ryan E., Pearce, Margaret M. P., Shaler, Thomas A., Olzmann, James A., Greenblatt, Ethan J., Kopito, Ron R.
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521676/
https://ncbi.nlm.nih.gov/pubmed/23097496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-06-0428
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