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A semi-supervised boosting SVM for predicting hot spots at protein-protein Interfaces
BACKGROUND: Hot spots are residues contributing the most of binding free energy yet accounting for a small portion of a protein interface. Experimental approaches to identify hot spots such as alanine scanning mutagenesis are expensive and time-consuming, while computational methods are emerging as...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3521187/ https://ncbi.nlm.nih.gov/pubmed/23282146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-S2-S6 |
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