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Enhanced Prediction of Hot Spots at Protein-Protein Interfaces Using Extreme Gradient Boosting

Identification of hot spots, a small portion of protein-protein interface residues that contribute the majority of the binding free energy, can provide crucial information for understanding the function of proteins and studying their interactions. Based on our previous method (PredHS), we propose a...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Hao, Liu, Chuyao, Deng, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155324/
https://ncbi.nlm.nih.gov/pubmed/30250210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32511-1
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