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Enhanced Prediction of Hot Spots at Protein-Protein Interfaces Using Extreme Gradient Boosting

Identification of hot spots, a small portion of protein-protein interface residues that contribute the majority of the binding free energy, can provide crucial information for understanding the function of proteins and studying their interactions. Based on our previous method (PredHS), we propose a...

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Pubblicato in:Sci Rep
Autori principali: Wang, Hao, Liu, Chuyao, Deng, Lei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155324/
https://ncbi.nlm.nih.gov/pubmed/30250210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32511-1
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