Inhibition of Influenza Virus Ribonucleic Acid Polymerase by Ribavirin Triphosphate

Ribavirin 5′-triphosphate (RTP), derived from the broad-spectrum antiviral compound ribavirin (Virazole), can selectively inhibit influenza virus ribonucleic acid polymerase in a cell-free assay. Ribavirin and its 5′-monophosphate have no effect on the polymerase. The inhibition is competitive with...

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Bibliografische gegevens

Gepubliceerd in:	Antimicrob Agents Chemother
Hoofdauteurs:	Eriksson, Bertil, Helgstrand, Erik, Johansson, Nils Gunnar, Larsson, Alf, Misiorny, Alfons, Noren, Jan Olof, Philipson, Lennart, Stenberg, Kjell, Stening, Goran, Stridh, Stig, Öberg, Bo
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Microbiology (ASM) 1977
Onderwerpen:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352108/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/879760/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.11.6.946
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