A Sialyltransferase Mutant with Decreased Donor Hydrolysis and Reduced Sialidase Activities for Directly Sialylating Lewis(x)

Glycosyltransferases are important catalysts for enzymatic and chemoenzymatic synthesis of complex carbohydrates and glycoconjugates. The glycosylation efficiencies of wild-type glycosyltransferases vary considerably when different acceptor substrates were used. Using a multifunctional Pasteurella m...

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Bibliografiske detaljer
Main Authors: Sugiarto, Go, Lau, Kam, Qu, Jingyao, Li, Yanhong, Lim, Sunghyuk, Mu, Shengmao, Ames, James B., Fisher, Andrew J., Chen, Xi
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521065/
https://ncbi.nlm.nih.gov/pubmed/22583967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300125k
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