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Autophagy and Apoptosis Are Differentially Induced in Neurons and Astrocytes Treated with an In Vitro Mimic of the Ischemic Penumbra

The development of clinical stroke therapies remains elusive. The neuroprotective efficacies of thousands of molecules and compounds have not yet been determined; however, screening large volumes of potential targets in vivo is severely rate limiting. High throughput screens (HTS) may be used to dis...

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Detalhes bibliográficos
Main Authors: Pamenter, Matthew E., Perkins, Guy A., McGinness, Anelah K., Gu, Xiang Q., Ellisman, Mark H., Haddad, Gabriel G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3520810/
https://ncbi.nlm.nih.gov/pubmed/23251543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051469
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