DIDS Prevents Ischemic Membrane Degradation in Cultured Hippocampal Neurons by Inhibiting Matrix Metalloproteinase Release

During stroke, cells in the infarct core exhibit rapid failure of their permeability barriers, which releases ions and inflammatory molecules that are deleterious to nearby tissue (the penumbra). Plasma membrane degradation is key to penumbral spread and is mediated by matrix metalloproteinases (MMP...

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Main Authors: Pamenter, Matthew E., Ryu, Julie, Hua, Serena T., Perkins, Guy A., Mendiola, Vincent L., Gu, Xiang Q., Ellisman, Mark H., Haddad, Gabriel G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2012
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427179/
https://ncbi.nlm.nih.gov/pubmed/22937143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043995
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