Incorporation of paramagnetic, fluorescent and PET/SPECT contrast agents into liposomes for multimodal imaging

A series of metal-chelating lipid conjugates has been designed and synthesized. Each member of the series bears a 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) macrocycle attached to the lipid head group, using short n-ethylene glycol (n-EG) spacers of varying length. Liposomes inc...

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主要な著者: Mitchell, Nick, Kalber, Tammy L., Cooper, Margaret S., Sunassee, Kavitha, Chalker, Samantha L., Shaw, Karen P., Ordidge, Katherine L., Badar, Adam, Janes, Samuel M., Blower, Philip J., Lythgoe, Mark F., Hailes, Helen C., Tabor, Alethea B.
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier Science 2013
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3520009/
https://ncbi.nlm.nih.gov/pubmed/23131536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.09.070
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