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Incorporation of paramagnetic, fluorescent and PET/SPECT contrast agents into liposomes for multimodal imaging

A series of metal-chelating lipid conjugates has been designed and synthesized. Each member of the series bears a 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) macrocycle attached to the lipid head group, using short n-ethylene glycol (n-EG) spacers of varying length. Liposomes inc...

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Κύριοι συγγραφείς:	Mitchell, Nick, Kalber, Tammy L., Cooper, Margaret S., Sunassee, Kavitha, Chalker, Samantha L., Shaw, Karen P., Ordidge, Katherine L., Badar, Adam, Janes, Samuel M., Blower, Philip J., Lythgoe, Mark F., Hailes, Helen C., Tabor, Alethea B.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Elsevier Science 2013
Θέματα:	Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3520009/ https://ncbi.nlm.nih.gov/pubmed/23131536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.09.070
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Incorporation of paramagnetic, fluorescent and PET/SPECT contrast agents into liposomes for multimodal imaging

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