Incorporation of paramagnetic, fluorescent and PET/SPECT contrast agents into liposomes for multimodal imaging

A series of metal-chelating lipid conjugates has been designed and synthesized. Each member of the series bears a 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) macrocycle attached to the lipid head group, using short n-ethylene glycol (n-EG) spacers of varying length. Liposomes inc...

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Detaylı Bibliyografya
Asıl Yazarlar: Mitchell, Nick, Kalber, Tammy L., Cooper, Margaret S., Sunassee, Kavitha, Chalker, Samantha L., Shaw, Karen P., Ordidge, Katherine L., Badar, Adam, Janes, Samuel M., Blower, Philip J., Lythgoe, Mark F., Hailes, Helen C., Tabor, Alethea B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier Science 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3520009/
https://ncbi.nlm.nih.gov/pubmed/23131536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.09.070
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