Incorporation of paramagnetic, fluorescent and PET/SPECT contrast agents into liposomes for multimodal imaging

A series of metal-chelating lipid conjugates has been designed and synthesized. Each member of the series bears a 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) macrocycle attached to the lipid head group, using short n-ethylene glycol (n-EG) spacers of varying length. Liposomes inc...

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Bibliografski detalji
Glavni autori: Mitchell, Nick, Kalber, Tammy L., Cooper, Margaret S., Sunassee, Kavitha, Chalker, Samantha L., Shaw, Karen P., Ordidge, Katherine L., Badar, Adam, Janes, Samuel M., Blower, Philip J., Lythgoe, Mark F., Hailes, Helen C., Tabor, Alethea B.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier Science 2013
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3520009/
https://ncbi.nlm.nih.gov/pubmed/23131536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.09.070
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