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Convenient one-step synthesis of a medicinally relevant benzopyranopyridine system

Benzopyrano[2,3-b]pyridine is an important privileged medicinal scaffold. A three-component reaction of salicylaldehydes, thiols and 2 equiv of malononitrile that leads to the formation of a series of compounds incorporating 2,4-diamino-3-cyano-5-sulfanylbenzopyrano[2,3-b]pyridine framework is descr...

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Main Authors: Evdokimov, Nikolai M., Kireev, Artem S., Yakovenko, Andrey A., Antipin, Mikhail Yu., Magedov, Igor V., Kornienko, Alexander
格式: Artigo
語言:Inglês
出版: 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519924/
https://ncbi.nlm.nih.gov/pubmed/23243322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2006.10.110
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