MLH1 Region Polymorphisms Show a Significant Association with CpG Island Shore Methylation in a Large Cohort of Healthy Individuals

Single nucleotide polymorphisms (SNPs) are the most common form of genetic variation. We previously demonstrated that SNPs (rs1800734, rs749072, and rs13098279) in the MLH1 gene region are associated with MLH1 promoter island methylation, loss of MLH1 protein expression, and microsatellite instabili...

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Bibliografski detalji
Glavni autori: Savio, Andrea J., Lemire, Mathieu, Mrkonjic, Miralem, Gallinger, Steven, Zanke, Brent W., Hudson, Thomas J., Bapat, Bharati
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519863/
https://ncbi.nlm.nih.gov/pubmed/23240038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051531
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