Dietary Heme Alters Microbiota and Mucosa of Mouse Colon without Functional Changes in Host-Microbe Cross-Talk

Colon cancer is a major cause of cancer deaths in Western countries and is associated with diets high in red meat. Heme, the iron-porphyrin pigment of red meat, induces cytotoxicity of gut contents which injures surface cells leading to compensatory hyperproliferation of crypt cells. This hyperproli...

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Detalhes bibliográficos
Main Authors: IJssennagger, Noortje, Derrien, Muriel, van Doorn, Gerdien M., Rijnierse, Anneke, van den Bogert, Bartholomeus, Müller, Michael, Dekker, Jan, Kleerebezem, Michiel, van der Meer, Roelof
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519815/
https://ncbi.nlm.nih.gov/pubmed/23239972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049868
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