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Regulated protein aggregation: stress granules and neurodegeneration
The protein aggregation that occurs in neurodegenerative diseases is classically thought to occur as an undesirable, nonfunctional byproduct of protein misfolding. This model contrasts with the biology of RNA binding proteins, many of which are linked to neurodegenerative diseases. RNA binding prote...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2012
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3519755/ https://ncbi.nlm.nih.gov/pubmed/23164372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-7-56 |
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