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Regulated protein aggregation: stress granules and neurodegeneration

The protein aggregation that occurs in neurodegenerative diseases is classically thought to occur as an undesirable, nonfunctional byproduct of protein misfolding. This model contrasts with the biology of RNA binding proteins, many of which are linked to neurodegenerative diseases. RNA binding prote...

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Detalhes bibliográficos
Autor principal: Wolozin, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519755/
https://ncbi.nlm.nih.gov/pubmed/23164372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-7-56
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