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Regulated protein aggregation: stress granules and neurodegeneration

The protein aggregation that occurs in neurodegenerative diseases is classically thought to occur as an undesirable, nonfunctional byproduct of protein misfolding. This model contrasts with the biology of RNA binding proteins, many of which are linked to neurodegenerative diseases. RNA binding prote...

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Bibliografiske detaljer
Hovedforfatter: Wolozin, Benjamin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519755/
https://ncbi.nlm.nih.gov/pubmed/23164372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-7-56
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