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Physiological Protein Aggregation Run Amuck: Stress Granules and the Genesis of Neurodegenerative Disease

Recent advances in neurodegenerative diseases point to novel mechanisms of protein aggregation. RNA binding proteins are abundant in the nucleus, where they carry out processes such as RNA splicing. Neurons also express RNA binding proteins in the cytoplasm and processes to enable functions such as...

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Detalhes bibliográficos
Publicado no:Discov Med
Autor principal: Wolozin, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694572/
https://ncbi.nlm.nih.gov/pubmed/24411700
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