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Evolutionary Diversity of the Mitochondrial Calcium Uniporter
Calcium uptake into mitochondria occurs via a recently identified ion channel called the uniporter. Here, we characterize the phylogenomic distribution of the uniporter’s membrane-spanning pore subunit (MCU) and regulatory partner (MICU1). Homologs of both components tend to co-occur in all major br...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3518847/ https://ncbi.nlm.nih.gov/pubmed/22605770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1214977 |
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