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Systematic Evaluation of the Dependence of Deoxyribozyme Catalysis on Random Region Length

Functional nucleic acids are DNA and RNA aptamers that bind targets, or they are deoxyribozymes and ribozymes that have catalytic activity. These functional DNA and RNA sequences can be identified from random-sequence pools by in vitro selection, which requires choosing the length of the random regi...

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Detalhes bibliográficos
Main Authors: Velez, Tania E., Singh, Jaydeep, Xiao, Ying, Allen, Emily C., Wong, On Yi, Chandra, Madhavaiah, Kwon, Sarah C., Silverman, Scott K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518697/
https://ncbi.nlm.nih.gov/pubmed/23088677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/co300111f
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