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Maintenance of Hematopoietic Stem Cells through Regulation of Wnt and mTOR Pathways

Hematopoietic stem cell (HSC) self-renewal and lineage commitment depend on complex interactions with the microenvironment, and the ability to maintain or expand HSCs for clinical applications or for basic research has been significantly limited because these interactions are not well defined. Recen...

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Autores principales: Huang, Jian, Nguyen-McCarty, Michelle, Hexner, Elizabeth O., Danet-Desnoyers, Gwenn, Klein, Peter S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518679/
https://ncbi.nlm.nih.gov/pubmed/23142822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2984
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