UpSET recruits HDAC complexes and restricts chromatin accessibility and histone acetylation at promoter regions

Developmental gene expression results from the orchestrated interplay between genetic and epigenetic mechanisms. Here we describe upSET, a transcriptional regulator encoding a SET domain-containing protein recruited to active and inducible genes in Drosophila. However, unlike other Drosophila SET pr...

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Main Authors: Rincon-Arano, Hector, Halow, Jessica, Delrow, Jeffrey J., Parkhurst, Susan M., Groudine, Mark
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518625/
https://ncbi.nlm.nih.gov/pubmed/23177352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.11.009
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